The Big Bang Theory
Sheldon is thrown for a serious loop when his life begins to change in the season finale, The Status Quo Combustion. Penny and Leonard prepare to move in together and the comic-book store suffers a fire. CBS/CTV, 7 p.m.
In the season finale, The Grand Experiment, Mycroft is back in the lives of Sherlock and Joan. As the two sleuths track down leads and clues to their most recent case, Sherlock's brother complicates things. CBS/Global, 9 p.m.
Prepare for some shocking and dramatic twists and turns in the season finale, Fear (of the Unknown). This will be Sandra Oh's final appearance on the show, so fans are eager to discover how her character, Cristina, will be written out of the story. ABC/CTV, 8 p.m.
George Stroumboulopoulos: Dave Foley
David Letterman: Adam Sandler
Jimmy Fallon: Jennifer Lawrence, Craig Robinson
Jimmy Kimmel: Shailene Woodley, Aasif Mandvi
Craig Ferguson: Alfred Molina, Bianca Kajlich
Seth Meyers: Maya Rudolph, Lake Bell
Jon Stewart: Jim Parsons
Conan O'Brien: Ray Romano, Tom Felton