Texans 29 Colts 17
HOUSTON -- The Houston Texans are AFC South champions for the second straight year.
Andre Johnson had 151 yards receiving and a touchdown, Bryan Braman scored on a blocked punt and Shayne Graham kicked five field goals.
The Texans (12-2) grabbed their first AFC South title last season after the Colts nosedived without injured quarterback Peyton Manning. Manning is gone and Andrew Luck couldn't do much against Houston's defence.
The Colts (9-5) had won three straight and needed a win to clinch a playoff berth a year after going 2-14.
J.J. Watt had three sacks as Houston's defence got back on track a week after a 42-14 loss to New England.
The Texans will have home-field advantage throughout the AFC playoffs if they win out.
Redskins 38 Browns 21
CLEVELAND -- Rookie Kirk Cousins threw for 329 yards and two touchdowns filling in for injured star Robert Griffin III, leading Washington to its fifth straight win.
Cousins connected with Leonard Hankerson for both TDs in his first career start and the Redskins (8-6) barely missed a beat without the talented and multi-dimensional RG3, who sat out with a sprained knee.
Last week, Cousins came off the bench after Griffin got hurt. Cousins was behind centre from the start of this one and delivered a performance that extended Washington's longest winning streak since 2007 and moved the Redskins into a tie for first in the NFC East.
Rookie Trent Richardson had a pair of TD runs for the Browns (5-9).
Seahawks 50 Bills 17
TORONTO -- Seattle rookie quarterback Russell Wilson ran for three touchdowns and threw for another in leading the Seahawks to their second straight rout.
Wilson scored on runs of 14, 25 and four yards and then hit Zach Miller for a four-yard touchdown in helping the Seahawks score 31 points on their first five possessions. The defence forced three consecutive turnovers to start the second half, including Earl Thomas scoring on 57-yard interception return.
A week after a 58-0 win at home against Arizona, the Seahawks (9-5) inched closer to clinching a playoff berth and became the NFL's third team to score 50 points on consecutive weekends. The Bills (5-9) were knocked out of playoff contention for a 13th consecutive season.
Cowboys 27 Steelers 24 OT
ARLINGTON, Texas -- Brandon Carr intercepted a pass from Ben Roethlisberger to set up Dan Bailey's 21-yard field goal in overtime.
The Cowboys won on a Bailey kick on the final play for the second straight week since practice squad linebacker Jerry Brown was killed in a one-car accident that led to manslaughter charges against teammate Josh Brent.
Carr intercepted Roethlisberger's pass along the sideline and returned it 36 yards to the one. Bailey's kick came after Tony Romo took a two-yard loss to put the kicker in better position.
The Cowboys (8-6) moved into a three-way tie for the NFC East lead with the Giants and Redskins. The Steelers (7-7) lost for the fourth time in five games.
Cardinals 31 Lions 10
GLENDALE, Ariz. -- Greg Toler returned an interception 102 yards for a fourth-quarter touchdown as Arizona ended a nine-game losing streak.
The Cardinals (5-9) intercepted Matthew Stafford three times, returning two for touchdowns and setting up a TD with the other. The Lions (4-10) lost their sixth straight. Rashad Johnson brought back a pick 53 yards for a touchdown to cap Arizona's 21-point second quarter. Patrick Peterson's interception set up another score.
Detroit's Calvin Johnson became the first player in NFL history with consecutive 1,600-yard receiving seasons and tied an NFL record with his seventh straight 100-yard receiving game.
Panthers 31 Chargers 7
SAN DIEGO -- Mike Tolbert scored twice against his former team and DeAngelo Williams turned a tipped pass from Cam Newton into a 45-yard touchdown reception.
Carolina (5-9) won consecutive games for the first time since last December. The loss knocked the Chargers out of playoff contention for the third straight year.
The Chargers (5-9) clinched their first losing season since 2003, when they were an NFL-worst 4-12. Coach Norv Turner is expected to be fired at season's end, most likely along with general manager A.J. Smith.
Tolbert capped Carolina's first two drives with one-yard scoring runs. His second TD was set up when Philip Rivers lost a fumble, his 21st turnover this season and 46th in less than two full seasons.
Saints 41 Buccaneers 0
NEW ORLEANS -- Drew Brees passed for 307 yards and four touchdowns, and New Orleans posted its first shutout since 1995.
Brees connected on his scoring passes with tight end David Thomas, running back Darren Sproles and receivers Lance Moore and Joe Morgan. Mark Ingram added an 11-yard touchdown run.
Josh Freeman endured one of his worst outings of the season for Tampa Bay (6-8), throwing four interceptions and losing a fumble. Jabari Greer made two interceptions, Rafael Bush and Isa Abdul-Quddus the others. Cameron Jordan forced Freeman's fumble on a sack and recovered it.
New Orleans (6-8) also bottled up standout rookie running back Doug Martin, holding him to 16 yards on nine carries.
Dolphins 24 Jaguars 3
MIAMI -- Miami kept former teammate Chad Henne out of the end zone, made three fourth-down stops deep in its own territory and benefited from an odd penalty.
Henne, playing in Miami for the first time since he departed as a Dolphins bust last off-season, threw for 221 yards with no turnovers. But the Dolphins turned back three scoring threats, and a go-ahead touchdown for the Jaguars came off the board because of an illegal-substitution penalty.
Ryan Tannehill went 22 for 28 for 220 yards and two scores with no interceptions to help Miami (6-8). The Jaguars (2-12) helped their chances of getting the No. 1 draft pick next April.
Raiders 15 Chiefs 0
OAKLAND, Calif. -- Sebastian Janikowski kicked five field goals and Darren McFadden rushed for 110 yards.
The Raiders (4-10) overwhelmed the Chiefs (2-12) to snap a six-game losing streak. Sandwiched around those losses are a pair of wins over Kansas City, a rare bright spot in this disappointing season in Oakland.
There has been little to cheer for this season for the Chiefs, who have lost 10 of 11 games and are tied for the second most losses in franchise history behind a 2-14 mark in 2008.
49ers 41 Patriots 34
FOXBOROUGH, Mass. -- The San Francisco 49ers earned a playoff berth by withstanding a stunning comeback by New England from a 28-point deficit to beat the Patriots 41-34 on Sunday night in the rain.
Michael Crabtree took a short pass and sped around cornerback Kyle Arrington for a 38-yard touchdown with 6:25 to go, then David Akers made a 28-yard field goal to clinch it.
New England (10-4) trailed 31-3 at one point and lost for the first time at home in December in 21 games. They also had won 21 in a row in the second half of the schedule before San Francisco (10-3-1) somehow regrouped late in a game it seemingly had clinched long before.
-- The Associated Press