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New Research Explores Genetic Factors Behind Adverse Reactions to Antidepressants in Young Canadians
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Hey there, time traveller!
This article was published 21/03/2025 (225 days ago), so information in it may no longer be current.
Antidepressants, including selective serotonin reuptake inhibitors (SSRIs), are among the most prescribed mental health medications for Canadian youth. While SSRIs are generally considered safe and effective, some children experience adverse effects such as hyperactivity, impulsivity, or irritability.
Dr. Abdullah Al Maruf, Assistant Professor of clinical pharmacogenomics at the College of Pharmacy, University of Manitoba, in collaboration with Dr. Laurence Katz, Professor of psychiatry, are investigating the genetic variants that may predict the likelihood of these adverse effects. By comparing the genetic profiles of youth who tolerate SSRIs well with those who don’t, the research aims to identify genetic markers linked to these side effects.
The study will also empower clinicians to provide more personalized and effective treatment for young patients at Health Sciences Centre, improving their mental health care. For more information, visit maruf-lab.org/pgx-simba.html.
This essential research is supported by a $70,000 HSC Foundation Grant. In 2024, thanks to the generosity of donors, the HSC Foundation invested $215,000 in critical health care research. To support life-changing research, donate at hscfoundation.mb.ca or call 204-515-5612.
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